CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.472 | Cyclin A; domain 1 |
|
1.10.472.20 | Nitrile hydratase, beta subunit |
Domain Context
CATH Clusters
| Superfamily | Nitrile hydratase, beta subunit |
| Functional Family | Cobalt-containing nitrile hydratase subunit beta |
Enzyme Information
| 4.2.1.84 |
Nitrile hydratase.
based on mapping to UniProt Q7SID3
An aliphatic amide = a nitrile + H(2)O.
-!- Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides. -!- Does not act on these amides or on aromatic nitriles (cf. EC 3.5.5.1).
|
UniProtKB Entries (1)
| Q7SID2 |
NHAA_PSETH
Pseudonocardia thermophila
Cobalt-containing nitrile hydratase subunit alpha
|
PDB Structure
| PDB | 4OB2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile.
J.Am.Chem.Soc.
|
