CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.132 | Topoisomerase I; Chain A, domain 4 |
|
1.10.132.70 |
Domain Context
CATH Clusters
| Superfamily | 1.10.132.70 |
| Functional Family | Telomerase reverse transcriptase |
Enzyme Information
| 2.7.7.49 |
RNA-directed DNA polymerase.
based on mapping to UniProt Q1PS67
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a RNA or DNA primer. -!- DNA can also serve as template. -!- See also EC 2.7.7.7.
|
UniProtKB Entries (1)
| Q1PS67 |
TERT_ORYLA
Oryzias latipes
Telomerase reverse transcriptase
|
PDB Structure
| PDB | 4O26 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for protein-RNA recognition in telomerase.
Nat.Struct.Mol.Biol.
|
