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1 keywords

CATH Domain 4mz5E00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.25 Alpha Horseshoe
Topology 1.25.10 Leucine-rich Repeat Variant
Homologous Superfamily 1.25.10.10 Leucine-rich Repeat Variant

Domain Context

CATH Clusters

Superfamily Leucine-rich Repeat Variant
Functional Family Importin subunit alpha

Enzyme Information

UniProtKB Entries (2)

P52293
IMA1_MOUSE
Mus musculus
Importin subunit alpha-1
P33316
DUT_HUMAN
Homo sapiens
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

PDB Structure

PDB 4MZ5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Rona, G., Marfori, M., Borsos, M., Scheer, I., Takacs, E., Toth, J., Babos, F., Magyar, A., Erdei, A., Bozoky, Z., Buday, L., Kobe, B., Vertessy, B.G.
Acta Crystallogr.,Sect.D
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