CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.180 | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 |
|
3.10.180.10 | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 |
| Functional Family | Lactoylglutathione lyase |
Enzyme Information
| 4.4.1.5 |
Lactoylglutathione lyase.
based on mapping to UniProt Q9CPU0
(R)-S-lactoylglutathione = glutathione + methylglyoxal.
-!- Also acts on 3-phosphoglycerol-glutathione.
|
UniProtKB Entries (1)
| Q9CPU0 |
LGUL_MOUSE
Mus musculus
Lactoylglutathione lyase
|
PDB Structure
| PDB | 4KYK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Zopolrestat as a Human Glyoxalase I Inhibitor and Its Structural Basis
Chemmedchem
|
