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1 keywords

CATH Domain 4kngM00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.10 Ribbon
Topology 2.10.220 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2
Homologous Superfamily 2.10.220.10 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2

Domain Context

CATH Clusters

Superfamily Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2
Functional Family R-spondin 3

Enzyme Information

UniProtKB Entries (1)

Q68DV7
RNF43_HUMAN
Homo sapiens
E3 ubiquitin-protein ligase RNF43

PDB Structure

PDB 4KNG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The structural basis of R-spondin recognition by LGR5 and RNF43.
Chen, P.H., Chen, X., Lin, Z., Fang, D., He, X.
Genes Dev.
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