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CATH Domain 4k6nA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.10 D-amino Acid Aminotransferase; Chain A, domain 2
Homologous Superfamily 3.20.10.10 D-amino Acid Aminotransferase, subunit A, domain 2

Domain Context

CATH Clusters

Superfamily D-amino Acid Aminotransferase, subunit A, domain 2
Functional Family Aminodeoxychorismate lyase

Enzyme Information

4.1.3.38
Aminodeoxychorismate lyase.
based on mapping to UniProt Q03266
4-amino-4-deoxychorismate = 4-aminobenzoate + pyruvate.
-!- Forms part of the folate biosynthesis pathway. -!- Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate.

UniProtKB Entries (1)

Q03266
PABC_YEAST
Saccharomyces cerevisiae S288C
Aminodeoxychorismate lyase

PDB Structure

PDB 4K6N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and catalytic mechanism of yeast 4-amino-4-deoxychorismate lyase
Dai, Y.-N., Chi, C.-B., Zhou, K., Cheng, W., Jiang, Y.-L., Ren, Y.-M., Ruan, K., Chen, Y., Zhou, C.-Z.
J.Biol.Chem.
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