CATH Domain 4jfnA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.570	Sugar Binding Protein, Amyloid A4 Protein; Chain A
	3.90.570.10	Amyloidogenic glycoprotein, heparin-binding domain

Domain Context

CATH Clusters

Superfamily	Amyloidogenic glycoprotein, heparin-binding domain
Functional Family	Amyloid beta A4 protein

Enzyme Information

UniProtKB Entries (1)

A4_HUMAN

Homo sapiens

Amyloid-beta precursor protein

PDB Structure

PDB	4JFN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain Baumkotter, F., Schmidt, N., Vargas, C., Schilling, S., Weber, R., Wagner, K., Fiedler, S., Klug, W., Radzimanowski, J., Nickolaus, S., Keller, S., Eggert, S., Wild, K., Kins, S. J.Neurosci.