CATH Domain 4j8sA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.840	CCR4-NOT transcription complex subunit 1 TTP binding domain

Domain Context

CATH Clusters

Superfamily	CCR4-NOT transcription complex subunit 1 TTP binding domain
Functional Family	Ccr4-not transcription complex subunit 1 isoform

Enzyme Information

UniProtKB Entries (1)

TTP_HUMAN

Homo sapiens

MRNA decay activator protein ZFP36

PDB Structure

PDB	4J8S
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin. Fabian, M.R., Frank, F., Rouya, C., Siddiqui, N., Lai, W.S., Karetnikov, A., Blackshear, P.J., Nagar, B., Sonenberg, N. Nat.Struct.Mol.Biol.