CATH Domain 4iqyB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.220	Leucine Aminopeptidase, subunit E; domain 1
	3.40.220.10	Leucine Aminopeptidase, subunit E, domain 1

Domain Context

CATH Clusters

Superfamily	Leucine Aminopeptidase, subunit E, domain 1
Functional Family	O-acetyl-ADP-ribose deacetylase MACROD2

Enzyme Information

3.5.1.-	In linear amides. based on mapping to UniProt A1Z1Q3
3.2.2.-	Hydrolyzing N-glycosyl compounds. based on mapping to UniProt A1Z1Q3

UniProtKB Entries (1)

MACD2_HUMAN

Homo sapiens

ADP-ribose glycohydrolase MACROD2

PDB Structure

PDB	4IQY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A family of macrodomain proteins reverses cellular mono-ADP-ribosylation. Jankevicius, G., Hassler, M., Golia, B., Rybin, V., Zacharias, M., Timinszky, G., Ladurner, A.G. Nat.Struct.Mol.Biol.