CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| A7LCX1 |
A7LCX1_PIG
Sus scrofa
Interferon-induced helicase C domain-containing protein 1
|
| P11207 |
V_PIV5
Simian virus 5 (strain W3)
Non-structural protein V
|
PDB Structure
| PDB | 4I1S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.
Science
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