CATH Domain 4i01B02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	cAMP-activated global transcriptional regulator CRP

Enzyme Information

UniProtKB Entries (1)

CRP_ECOLI

Escherichia coli K-12

CAMP-activated global transcriptional regulator CRP

PDB Structure

PDB	4I01
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Rodgers, T.L., Townsend, P.D., Burnell, D., Jones, M.L., Richards, S.A., McLeish, T.C., Pohl, E., Wilson, M.R., Cann, M.J. Plos Biol.