CATH Domain 4htiA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.2470	Protein-tyrosine phosphatase receptor IA-2 ectodomain

Domain Context

CATH Clusters

Superfamily	Protein-tyrosine phosphatase receptor IA-2 ectodomain
Functional Family	receptor-type tyrosine-protein phosphatase-like N isoform X1

Enzyme Information

3.1.3.48	Protein-tyrosine-phosphatase. based on mapping to UniProt Q92932 Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. -!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
3.1.3.-	Phosphoric monoester hydrolases. based on mapping to UniProt Q92932

UniProtKB Entries (1)

PTPR2_HUMAN

Homo sapiens

Receptor-type tyrosine-protein phosphatase N2

PDB Structure

PDB	4HTI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	X-ray structure of the mature ectodomain of phogrin. Noguera, M.E., Primo, M.E., Jakoncic, J., Poskus, E., Solimena, M., Ermacora, M.R. J.Struct.Funct.Genom.