CATH Domain 4hlyB00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	VIRF-1

Enzyme Information

UniProtKB Entries (1)

VIRF1_HHV8P

Human herpesvirus 8 strain GK18

VIRF-1

PDB Structure

PDB	4HLY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor. Hew, K., Dahlroth, S.L., Venkatachalam, R., Nasertorabi, F., Lim, B.T., Cornvik, T., Nordlund, P. Nucleic Acids Res.