CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.720 | Alkaline Phosphatase, subunit A |
|
3.40.720.10 | Alkaline Phosphatase, subunit A |
Domain Context
CATH Clusters
| Superfamily | Alkaline Phosphatase, subunit A |
| Functional Family | Galactosamine (N-acetyl)-6-sulfatase |
Enzyme Information
| 3.1.6.4 |
N-acetylgalactosamine-6-sulfatase.
based on mapping to UniProt P34059
Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.
|
UniProtKB Entries (1)
| P34059 |
GALNS_HUMAN
Homo sapiens
N-acetylgalactosamine-6-sulfatase
|
PDB Structure
| PDB | 4FDJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV A.
J.Mol.Biol.
|
