CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Ribosomal RNA large subunit methyltransferase G

Enzyme Information

2.1.1.174
23S rRNA (guanine(1835)-N(2))-methyltransferase.
based on mapping to UniProt P42596
S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(1835) in 23S rRNA.
-!- The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. -!- The enzyme specifically methylates guanine(1835) at N(2) in 23S rRNA. -!- Formerly EC 2.1.1.52.

UniProtKB Entries (1)

P42596
RLMG_ECOLI
Escherichia coli K-12
Ribosomal RNA large subunit methyltransferase G

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
CATH-Gene3D is a Global Biodata Core Resource Learn more...