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CATH Classification

Domain Context

CATH Clusters

Superfamily Citrate Synthase, domain 1
Functional Family Citrate synthase

Enzyme Information

2.3.3.1
Citrate (Si)-synthase.
based on mapping to UniProt P00889
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
-!- The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes. -!- Citrate synthase for which the stereospecificity with respect to C(2) of oxaloacetate has not been established are included in EC 2.3.3.16. -!- Formerly EC 4.1.3.7.

UniProtKB Entries (1)

P00889
CISY_PIG
Sus scrofa
Citrate synthase, mitochondrial

PDB Structure

PDB 4CTS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure analysis and molecular model of a complex of citrate synthase with oxaloacetate and S-acetonyl-coenzyme A
Wiegand, G., Remington, S., Deisenhofer, J., Huber, R.
J.Mol.Biol.
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