CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.2020 | NE0471 N-terminal domain-like |
|
3.30.2020.30 |
Domain Context
CATH Clusters
| Superfamily | 3.30.2020.30 |
| Functional Family | Putative gamma-butyrobetaine dioxygenase |
Enzyme Information
| 1.14.11.1 |
Gamma-butyrobetaine dioxygenase.
based on mapping to UniProt O75936
4-trimethylammoniobutanoate + 2-oxoglutarate + O(2) = 3-hydroxy-4- trimethylammoniobutanoate + succinate + CO(2).
|
UniProtKB Entries (1)
| O75936 |
BODG_HUMAN
Homo sapiens
Gamma-butyrobetaine dioxygenase
|
PDB Structure
| PDB | 4C8R |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Modulating carnitine levels by targeting its biosynthesis pathway - selective inhibition of gamma-butyrobetaine hydroxylase.
Chem Sci
|
