CATH Domain 4b6vA00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.760	RNA Cap, Translation Initiation Factor Eif4e
	3.30.760.10	RNA Cap, Translation Initiation Factor Eif4e

Domain Context

CATH Clusters

Superfamily	RNA Cap, Translation Initiation Factor Eif4e
Functional Family	Eukaryotic translation initiation factor 4E family member 3

Enzyme Information

UniProtKB Entries (1)

IF4E3_MOUSE

Mus musculus

Eukaryotic translation initiation factor 4E type 3

PDB Structure

PDB	4B6V
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Eif4E3 Acts as a Tumor Suppressor by Utilizing an Atypical Mode of Methyl-7-Guanosine CAP Recognition. Osborne, M.J., Volpon, L., Kornblatt, J.A., Culjkovic-Kraljacic, B., Baguet, A., Borden, K.L.B. Proc.Natl.Acad.Sci.USA