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CATH Classification

Domain Context

CATH Clusters

Superfamily Helix hairpin bin
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P61875
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P61875
DPOL_PYRFU
Pyrococcus furiosus DSM 3638
DNA polymerase

PDB Structure

PDB 4AIL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of an Apo and a Binary Complex of an Evolved Archeal B Family DNA Polymerase Capable of Synthesising Highly Cy-Dye Labelled DNA.
Wynne, S.A., Pinheiro, V.B., Holliger, P., Leslie, A.G.
Plos One
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