CATH Domain 421pA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

RASH_HUMAN

Homo sapiens

GTPase HRas

PDB Structure

PDB	421P
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules. Krengel, U., Schlichting, I., Scherer, A., Schumann, R., Frech, M., John, J., Kabsch, W., Pai, E.F., Wittinghofer, A. Cell(Cambridge,Mass.)