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1 keywords

CATH Domain 3zgfA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.550 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Homologous Superfamily 3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family Histo-blood group ABO system transferase

Enzyme Information

2.4.1.37
Fucosylgalactoside 3-alpha-galactosyltransferase.
based on mapping to UniProt P16442
UDP-alpha-D-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = UDP + alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R.
-!- Acts on blood group substance, and can use a number of 2-fucosyl- galactosides as acceptors.
2.4.1.40
Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase.
based on mapping to UniProt P16442
UDP-N-acetyl-alpha-beta-D-galactosamine + glycoprotein-alpha-L-fucosyl- (1->2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl- (1->3)-(alpha-L-fucosyl-(1->2))-beta-D-galactose.
-!- Acts on blood group substance H. -!- Can use a number of 2-fucosyl-galactosides as acceptors.

UniProtKB Entries (1)

P16442
BGAT_HUMAN
Homo sapiens
Histo-blood group ABO system transferase

PDB Structure

PDB 3ZGF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations
Jorgensen, R., Batot, G., Mannerstedt, K., Imberty, A., Breton, C., Hindsgaul, O., Royant, A., Palcic, M.M.
Acta Crystallogr.,Sect.F
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