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1 keywords

CATH Domain 3waxA02

CATH Classification

Level CATH Code Description
Class 4 Few Secondary Structures
Architecture 4.10 Irregular
Topology 4.10.410 Factor Xa Inhibitor
Homologous Superfamily 4.10.410.20  

Domain Context

CATH Clusters

Superfamily 4.10.410.20
Functional Family Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Enzyme Information

3.1.4.39
Alkylglycerophosphoethanolamine phosphodiesterase.
based on mapping to UniProt Q9R1E6
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.
-!- Also acts on acyl and choline analogs.

UniProtKB Entries (1)

Q9R1E6
ENPP2_MOUSE
Mus musculus
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

PDB Structure

PDB 3WAX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Kawaguchi, M., Okabe, T., Okudaira, S., Nishimasu, H., Ishitani, R., Kojima, H., Nureki, O., Aoki, J., Nagano, T.
Acs Chem.Biol.
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