CATH Domain 3vv2B00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.80	Peptidase S8 propeptide/proteinase inhibitor I9

Domain Context

CATH Clusters

Superfamily	Peptidase S8 propeptide/proteinase inhibitor I9
Functional Family

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt P58502

UniProtKB Entries (1)

TKSU_THEKO

Thermococcus kodakarensis KOD1

Tk-subtilisin

PDB Structure

PDB	3VV2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Accelerated maturation of Tk-subtilisin by a Leu Pro mutation at the C-terminus of the propeptide, which reduces the binding of the propeptide to Tk-subtilisin Uehara, R., Ueda, Y., You, D.J., Koga, Y., Kanaya, S. Febs J.