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1 keywords

CATH Domain 3t1gA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.140 Metal-dependent hydrolases

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family Adenosine deaminase

Enzyme Information

3.5.4.4
Adenosine deaminase.
based on mapping to UniProt P03958
Adenosine + H(2)O = inosine + NH(3).

UniProtKB Entries (1)

P03958
ADA_MOUSE
Mus musculus
Adenosine deaminase

PDB Structure

PDB 3T1G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.
Khare, S.D., Kipnis, Y., Greisen, P.J., Takeuchi, R., Ashani, Y., Goldsmith, M., Song, Y., Gallaher, J.L., Silman, I., Leader, H., Sussman, J.L., Stoddard, B.L., Tawfik, D.S., Baker, D.
Nat.Chem.Biol.
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