CATH Domain 3sbxA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.450

Domain Context

CATH Clusters

Superfamily	3.40.50.450
Functional Family

Enzyme Information

3.2.2.n1

Cytokinin riboside 5'-monophosphate phosphoribohydrolase.

based on mapping to UniProt B2HS63

(1) N(6)-(Delta(2)-isopentenyl)-adenosine 5'-phosphate + H(2)O = N(6)- (dimethylallyl)adenine + D-ribose 5'-phosphate. (2) Trans-zeatin riboside phosphate + H(2)O = trans-zeatin + D-ribose 5'-phosphate.

-!- The enzyme, isolated from plants, is involved in the activation of cytokinins (such as N(6)-(dimethylallyl)adenine and trans-zeatin) plant hormones that are important for meristem activity.

UniProtKB Entries (1)

B2HS63

LOGH_MYCMM

Mycobacterium marinum M

Cytokinin riboside 5'-monophosphate phosphoribohydrolase

PDB Structure

PDB	3SBX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Increasing the structural coverage of tuberculosis drug targets. Baugh, L., Phan, I., Begley, D.W., Clifton, M.C., Armour, B., Dranow, D.M., Taylor, B.M., Muruthi, M.M., Abendroth, J., Fairman, J.W., Fox, D., Dieterich, S.H., Staker, B.L., Gardberg, A.S., Choi, R., Hewitt, S.N., Napuli, A.J., Myers, J., Barrett, L.K., Zhang, Y., Ferrell, M., Mundt, E., Thompkins, K., Tran, N., Lyons-Abbott, S., Abramov, A., Sekar, A., Serbzhinskiy, D., Lorimer, D., Buchko, G.W., Stacy, R., Stewart, L.J., Edwards, T.E., Van Voorhis, W.C., Myler, P.J. Tuberculosis (Edinb)

Network disruptions