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CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q86Y97
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q86Y97
KMT5C_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase KMT5C

PDB Structure

PDB 3RQ4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.
Wu, H., Siarheyeva, A., Zeng, H., Lam, R., Dong, A., Wu, X.H., Li, Y., Schapira, M., Vedadi, M., Min, J.
Febs Lett.
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