CATH Domain 3r9aC01

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.1150	Aspartate Aminotransferase, domain 1
	3.90.1150.10	Aspartate Aminotransferase, domain 1

Domain Context

CATH Clusters

Superfamily	Aspartate Aminotransferase, domain 1
Functional Family	Serine--pyruvate aminotransferase

Enzyme Information

2.6.1.51	Serine--pyruvate transaminase. based on mapping to UniProt P21549 L-serine + pyruvate = 3-hydroxypyruvate + L-alanine. -!- The liver enzyme may be identical with EC 2.6.1.44.
2.6.1.44	Alanine--glyoxylate transaminase. based on mapping to UniProt P21549 L-alanine + glyoxylate = pyruvate + glycine. -!- With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. -!- A second component also catalyzes the reaction of EC 2.6.1.51.

UniProtKB Entries (1)

PEX5_HUMAN

Homo sapiens

Peroxisomal targeting signal 1 receptor

PDB Structure

PDB	3R9A
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Molecular requirements for peroxisomal targeting of alanine-glyoxylate aminotransferase as an essential determinant in primary hyperoxaluria type 1 Fodor, K., Wolf, J., Erdmann, R., Schliebs, W., Wilmanns, M. Plos Biol.