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1 keywords

CATH Domain 3q7jB02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.390 Neutral Protease; domain 2
Homologous Superfamily 1.10.390.10 Neutral Protease Domain 2

Domain Context

CATH Clusters

Superfamily Neutral Protease Domain 2
Functional Family Puromycin-sensitive aminopeptidase

Enzyme Information

3.4.11.-
Aminopeptidases.
based on mapping to UniProt O93655

UniProtKB Entries (1)

O93655
TRF3_THEAC
Thermoplasma acidophilum DSM 1728
Tricorn protease-interacting factor F3

PDB Structure

PDB 3Q7J
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Engineered Thermoplasma acidophilum factor F3 mimics human aminopeptidase N (APN) as a target for anticancer drug development
Su, J., Wang, Q., Feng, J., Zhang, C., Zhu, D., Wei, T., Xu, W., Gu, L.
Bioorg.Med.Chem.
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