CATH Domain 3pnyB04

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.8	Helicase, Ruva Protein; domain 3
	1.10.8.70	Glutamate-tRNA synthetase, class I, anticodon-binding domain 1

Domain Context

CATH Clusters

Superfamily	Glutamate-tRNA synthetase, class I, anticodon-binding domain 1
Functional Family	Glutamate--tRNA ligase

Enzyme Information

6.1.1.17

Glutamate--tRNA ligase.

based on mapping to UniProt P9WFV9

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).

UniProtKB Entries (1)

SYE_MYCTU

Mycobacterium tuberculosis H37Rv

Glutamate--tRNA ligase

PDB Structure

PDB	3PNY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural analysis of the non-discriminating glutamyl-tRNA synthetase from Mycobacterium tuberculosis suggests minor role of anticodon recognition in tRNA(Gln) discrimination Laurinavichiute, D., Bruning, M., Shkolnaya, L.A., Bourenkov, G.P., Domanski, G., Konarev, P., Svergun, D., Strizhov, N.I., Kachalova, G.S., Bartunik, H.D. To be Published