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1 keywords

CATH Domain 3pkiE01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1220 TPP-binding domain

Domain Context

CATH Clusters

Superfamily TPP-binding domain
Functional Family NAD-dependent protein deacetylase sirtuin-6

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q8N6T7

UniProtKB Entries (1)

Q8N6T7
SIR6_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-6

PDB Structure

PDB 3PKI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and biochemical functions of SIRT6.
Pan, P.W., Feldman, J.L., Devries, M.K., Dong, A., Edwards, A.M., Denu, J.M.
J.Biol.Chem.
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