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1 keywords

CATH Domain 3nr9C02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.510 Transferase(Phosphotransferase); domain 1
Homologous Superfamily 1.10.510.10 Transferase(Phosphotransferase) domain 1

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Dual specificity protein kinase CLK2

Enzyme Information

2.7.12.1
Dual-specificity kinase.
based on mapping to UniProt P49760
ATP + a protein = ADP + a phosphoprotein.
-!- This family of enzymes can phosphorylate both Ser/Thr and Tyr residues. -!- Formerly EC 2.7.1.37.

UniProtKB Entries (1)

P49760
CLK2_HUMAN
Homo sapiens
Dual specificity protein kinase CLK2

PDB Structure

PDB 3NR9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human CDC2-like kinase 2 (CLK2)
Chaikuad, A., Savitsky, P., Krojer, T., Muniz, J.R.C., Filippakopoulos, P., Rellos, P., Keates, T., Fedorov, O., Pike, A.C.W., Eswaran, J., Berridge, G., Phillips, C., Zhang, Y., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
To be Published
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