CATH Classification

Domain Context

CATH Clusters

Superfamily Alanine racemase
Functional Family Carboxynorspermidine/carboxyspermidine decarboxylase

Enzyme Information

4.1.1.96
Carboxynorspermidine decarboxylase.
based on mapping to UniProt A8FNH9
(1) Carboxynorspermidine = bis(3-aminopropyl)amine + CO(2). (2) Carboxyspermidine = spermidine + CO(2).
-!- Part of a bacterial polyamine biosynthesis pathway. -!- The enzyme is essential for biofilm formation in the bacterium Vibrio cholerae. -!- The enzyme from Campylobacter jejuni only produces spermidine in vivo even though it shows activity with carboxynorspermidine in vitro.

UniProtKB Entries (1)

A8FNH9
NSPC_CAMJ8
Campylobacter jejuni subsp. jejuni 81116
Carboxynorspermidine/carboxyspermidine decarboxylase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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