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1 keywords

CATH Domain 3mypD00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Tagatose 1,6-diphosphate aldolase 2

Enzyme Information

4.1.2.40
Tagatose-bisphosphate aldolase.
based on mapping to UniProt Q5HE13
D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
-!- Enzyme activity is stimulated by certain divalent cations. -!- Involved in the tagatose 6-phosphate pathway of lactose catabolism in bacteria.

UniProtKB Entries (1)

Q5HE13
LACD_STAAC
Staphylococcus aureus subsp. aureus COL
Tagatose 1,6-diphosphate aldolase

PDB Structure

PDB 3MYP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of LacD from Staphylococcus aureus and LacD.1 from Streptococcus pyogenes: Insights into substrate specificity and virulence gene regulation
Lee, S.J., Kim, H.S., Kim, D.J., Yoon, H.J., Kim, K.H., Yoon, J.Y., Suh, S.W.
Febs Lett.
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