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1 keywords

CATH Domain 3lw8A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.300 P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Rho-related GTP-binding protein RhoC

Enzyme Information

UniProtKB Entries (2)

P61586
RHOA_HUMAN
Homo sapiens
Transforming protein RhoA
Q9AJW7
Q9AJW7_SHIFL
Shigella flexneri
IpgB2

PDB Structure

PDB 3LW8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry
Klink, B.U., Barden, S., Heidler, T.V., Borchers, C., Ladwein, M., Stradal, T.E.B., Rottner, K., Heinz, D.W.
J.Biol.Chem.
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