CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.1180 | Golgi alpha-mannosidase II |
Domain Context
CATH Clusters
| Superfamily | Golgi alpha-mannosidase II |
| Functional Family | Alpha-galactosidase |
Enzyme Information
| 3.2.1.49 |
Alpha-N-acetylgalactosaminidase.
based on mapping to UniProt P17050
Cleavage of non-reducing alpha-(1->3)-N-acetylgalactosamine residues from human blood group A and AB mucin glycoproteins, Forssman hapten and blood group A lacto series glycolipids.
-!- The human lysosomal enzyme is involved in the degradation of blood type A epitope.
|
UniProtKB Entries (1)
| P17050 |
NAGAB_HUMAN
Homo sapiens
Alpha-N-acetylgalactosaminidase
|
PDB Structure
| PDB | 3IGU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler and Kanzaki diseases
J.Mol.Biol.
|
