×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily D-amino Acid Aminotransferase, subunit A, domain 2
Functional Family Branched-chain-amino-acid aminotransferase

Enzyme Information

2.6.1.42
Branched-chain-amino-acid transaminase.
based on mapping to UniProt P9WQ75
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

UniProtKB Entries (1)

P9WQ75
ILVE_MYCTU
Mycobacterium tuberculosis H37Rv
Branched-chain-amino-acid aminotransferase

PDB Structure

PDB 3HT5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The 1.9 A structure of the branched-chain amino-acid transaminase (IlvE) from Mycobacterium tuberculosis.
Tremblay, L.W., Blanchard, J.S.
Acta Crystallogr.,Sect.F
CATH-Gene3D is a Global Biodata Core Resource Learn more...