CATH Domain 3gw6F04

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.5	Single alpha-helices involved in coiled-coils or other helix-helix interfaces
	1.20.5.100	Cytochrome c1, transmembrane anchor, C-terminal

Domain Context

CATH Clusters

Superfamily	Cytochrome c1, transmembrane anchor, C-terminal
Functional Family	Tail spike protein

Enzyme Information

3.2.1.129

Endo-alpha-sialidase.

based on mapping to UniProt Q04830

Endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.

-!- Although the name endo-N-acetylneuraminidase has also been used for this enzyme, this is misleading since its activity is not restricted to acetyl-substituted substrates. -!- An exo-alpha-sialidase activity is listed as EC 3.2.1.18. -!- See also 4.2.2.15.

UniProtKB Entries (1)

Q04830

FIBER_BPK1F

Enterobacteria phage K1F

Tail spike protein

PDB Structure

PDB	3GW6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of an intramolecular chaperone mediating triple-beta-helix folding. Schulz, E.C., Dickmanns, A., Urlaub, H., Schmitt, A., Muhlenhoff, M., Stummeyer, K., Schwarzer, D., Gerardy-Schahn, R., Ficner, R. Nat.Struct.Mol.Biol.

Network disruptions