CATH Domain 3gdfA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	NADP-dependent mannitol dehydrogenase

Enzyme Information

1.1.1.138

Mannitol 2-dehydrogenase (NADP(+)).

based on mapping to UniProt P0C0Y5

D-mannitol + NADP(+) = D-fructose + NADPH.

UniProtKB Entries (1)

MTDH_DAVTA

Cladosporium herbarum

NADP-dependent mannitol dehydrogenase

PDB Structure

PDB	3GDF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of the NADP-dependent mannitol dehydrogenase from Cladosporium herbarum: Implications for oligomerisation and catalysis. Nuss, D., Goettig, P., Magler, I., Denk, U., Breitenbach, M., Schneider, P.B., Brandstetter, H., Simon-Nobbe, B. Biochimie