CATH Classification

Domain Context

CATH Clusters

Superfamily Proprotein convertase subtilisin/kexin type 9
Functional Family Proprotein convertase subtilisin/kexin type 9

Enzyme Information

3.4.21.-
Serine endopeptidases.
based on mapping to UniProt Q8NBP7

UniProtKB Entries (1)

Q8NBP7
PCSK9_HUMAN
Homo sapiens
Proprotein convertase subtilisin/kexin type 9

PDB Structure

PDB 3GCW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
McNutt, M.C., Kwon, H.J., Chen, C., Chen, J.R., Horton, J.D., Lagace, T.A.
J.Biol.Chem.
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