CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1150 | Aspartate Aminotransferase, domain 1 |
|
3.90.1150.10 | Aspartate Aminotransferase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aspartate Aminotransferase, domain 1 |
| Functional Family | Kynureninase |
Enzyme Information
| 3.7.1.3 |
Kynureninase.
based on mapping to UniProt Q16719
L-kynurenine + H(2)O = anthranilate + L-alanine.
-!- Also acts on 3'-hydroxykynurenine and some other (3-arylcarbonyl)- alanines.
|
UniProtKB Entries (1)
| Q16719 |
KYNU_HUMAN
Homo sapiens
Kynureninase
|
PDB Structure
| PDB | 3E9K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity.
J.Med.Chem.
|
