CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.340 | Metallocarboxypeptidase-like |
Domain Context
CATH Clusters
| Superfamily | Metallocarboxypeptidase-like |
| Functional Family | Carboxypeptidase B2 |
Enzyme Information
| 3.4.17.20 |
Carboxypeptidase U.
based on mapping to UniProt Q96IY4
Release of C-terminal Arg and Lys from a polypeptide.
-!- Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U. -!- Activity similar to that of the more stable lysine carboxypeptidase, except no preference is shown for Lys over Arg. -!- Belongs to peptidase family M14.
|
UniProtKB Entries (1)
| Q96IY4 |
CBPB2_HUMAN
Homo sapiens
Carboxypeptidase B2
|
PDB Structure
| PDB | 3D66 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood
|
