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1 keywords

CATH Domain 3c90B00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.287 Helix Hairpins
Homologous Superfamily 1.10.287.1080 MazG-like

Domain Context

CATH Clusters

Superfamily MazG-like
Functional Family Phosphoribosyl-ATP pyrophosphatase

Enzyme Information

3.6.1.31
Phosphoribosyl-ATP diphosphatase.
based on mapping to UniProt P9WMM9
1-(5-phospho-beta-D-ribosyl)-ATP + H(2)O = 1-(5-phospho-beta-D-ribosyl)- AMP + diphosphate.
-!- The Neurospora crassa enzyme also catalyzes the reactions of EC 1.1.1.23 and EC 3.5.4.19.

UniProtKB Entries (1)

P9WMM9
HIS2_MYCTU
Mycobacterium tuberculosis H37Rv
Phosphoribosyl-ATP pyrophosphatase

PDB Structure

PDB 3C90
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Javid-Majd, F., Yang, D., Ioerger, T.R., Sacchettini, J.C.
Acta Crystallogr.,Sect.D
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