CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.600 | Farnesyl Diphosphate Synthase |
|
1.10.600.10 | Farnesyl Diphosphate Synthase |
Domain Context
CATH Clusters
| Superfamily | Farnesyl Diphosphate Synthase |
| Functional Family | Solanesyl diphosphate synthase 3, chloroplastic/mitochondrial |
Enzyme Information
| 2.5.1.85 |
All-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific).
based on mapping to UniProt Q5HZ00
Geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate.
-!- Geranylgeranyl diphosphate is preferred over farnesyl diphosphate as allylic substrate. -!- The plant Arabidopsis thaliana has two different enzymes that catalyze this reaction. -!- SPS1 contributes to the biosynthesis of the ubiquinone side-chain while SPS2 supplies the precursor of the plastoquinone side-chains. -!- Formerly EC 2.5.1.11.
|
UniProtKB Entries (1)
| Q5HZ00 |
SPS3_ARATH
Arabidopsis thaliana
Solanesyl diphosphate synthase 3, chloroplastic/mitochondrial
|
PDB Structure
| PDB | 3AQ0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase
Plant Physiol.
|
