CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.140 | Metal-dependent hydrolases |
Domain Context
CATH Clusters
| Superfamily | Metal-dependent hydrolases |
| Functional Family | 3',5'-nucleoside bisphosphate phosphatase |
Enzyme Information
| 3.1.3.97 |
3',5'-nucleoside bisphosphate phosphatase.
based on mapping to UniProt Q7NXD4
Nucleoside 3',5'-bisphosphate + H(2)O = nucleoside 5'-phosphate + phosphate.
-!- The enzyme, characterized from the bacterium Chromobacterium violaceum, has similar catalytic efficiencies with all the bases. -!- The enzyme has similar activity with ribonucleoside and 2'-deoxyribonucleoside 3',5'-bisphosphates, but shows no activity with nucleoside 2',5'-bisphosphates (cf. EC 3.1.3.7).
|
UniProtKB Entries (1)
| Q7NXD4 |
35NBP_CHRVO
Chromobacterium violaceum ATCC 12472
3',5'-nucleoside bisphosphate phosphatase
|
PDB Structure
| PDB | 2YB4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Prospecting for Unannotated Enzymes: Discovery of a 3',5'-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily.
Biochemistry
|
