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1 keywords

CATH Domain 2xqbH01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy variable 7-81 (non-functional)

Enzyme Information

UniProtKB Entries (1)

P40933
IL15_HUMAN
Homo sapiens
Interleukin-15

PDB Structure

PDB 2XQB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Engineering a High Affinity Anti-Il-15 Antibody: Crystal Structure Reveals an Alpha-Helix in Vh Cdr3 as Key Component of Paratope.
Lowe, D.C., Gerhardt, S., Ward, A., Hargreaves, D., Anderson, M., Ferraro, F., Pauptit, R.A., Pattison, D.V., Buchanan, C., Popovic, B., Finch, D.K., Wilkinson, T., Sleeman, M., Vaughan, T.J., Mallinder, P.R.
J.Mol.Biol.
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