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1 keywords

CATH Domain 2xbuB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2020  

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Xanthine phosphoribosyltransferase 1

Enzyme Information

2.4.2.8
Hypoxanthine phosphoribosyltransferase.
based on mapping to UniProt Q04178
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- Guanine and 6-mercaptopurine can replace hypoxanthine.

UniProtKB Entries (1)

Q04178
HPRT_YEAST
Saccharomyces cerevisiae S288C
Hypoxanthine-guanine phosphoribosyltransferase

PDB Structure

PDB 2XBU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
Moynie, L., Giraud, M.F., Breton, A., Boissier, F., Daignan-Fornier, B., Dautant, A.
Protein Sci.
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