CATH Domain 2rtuA00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.30	DNA Binding (I), subunit A
	1.10.30.10	High mobility group box domain

Domain Context

CATH Clusters

Superfamily	High mobility group box domain
Functional Family	High mobility group protein B1

Enzyme Information

UniProtKB Entries (1)

HMGB1_HUMAN

Homo sapiens

High mobility group protein B1

PDB Structure

PDB	2RTU
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Redox-sensitive structural change in the A-domain of HMGB1 and its implication for the binding to cisplatin modified DNA. Wang, J., Tochio, N., Takeuchi, A., Uewaki, J., Kobayashi, N., Tate, S. Biochem.Biophys.Res.Commun.