CATH Domain 2okkA01

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.1150	Aspartate Aminotransferase, domain 1
	3.90.1150.170

Superfamily	3.90.1150.170
Functional Family	Glutamate decarboxylase like 1

4.1.1.15

Glutamate decarboxylase.

based on mapping to UniProt Q05329

L-glutamate = 4-aminobutanoate + CO(2).

-!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.

DCE2_HUMAN

Homo sapiens

Glutamate decarboxylase 2

PDB	2OKK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Saccharomyces
Primary Citation	GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Fenalti, G., Law, R.H., Buckle, A.M., Langendorf, C., Tuck, K., Rosado, C.J., Faux, N.G., Mahmood, K., Hampe, C.S., Banga, J.P., Wilce, M., Schmidberger, J., Rossjohn, J., El-Kabbani, O., Pike, R.N., Smith, A.I., Mackay, I.R., Rowley, M.J., Whisstock, J.C. Nat.Struct.Mol.Biol.