CATH Domain 2nvuA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	NEDD8-activating enzyme E1 regulatory subunit

Enzyme Information

UniProtKB Entries (1)

ULA1_HUMAN

Homo sapiens

NEDD8-activating enzyme E1 regulatory subunit

PDB Structure

PDB	2NVU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity. Huang, D.T., Hunt, H.W., Zhuang, M., Ohi, M.D., Holton, J.M., Schulman, B.A. Nature