CATH Domain 2mh3B00

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CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.280	MYOD Basic-Helix-Loop-Helix Domain, subunit B
	4.10.280.10	Helix-loop-helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Helix-loop-helix DNA-binding domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

HES1_HUMAN

Homo sapiens

Transcription factor HES-1

PDB Structure

PDB	2MH3
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA. Popovic, M., Wienk, H., Coglievina, M., Boelens, R., Pongor, S., Pintar, A. Proteins